Find the Original
Start with a moderator guide, browse the wiki or filter by topic. Open the community source for its original wording, credits and revisions.
Start Here 7
The subreddit’s original orientation and moderator guides.
r/microdosing
Subreddit · The live community, announcements, discussion and rules.
The Official r/microdosing Starter’s Guide
Moderator guide · The original moderator post and graphic.
Open original Original moderator graphicsearch-indexedr/microdosing 101 · Version 1
Moderator guide · The original introductory guide linked by the sidebar.
r/microdosing 101 · Version 2
Moderator guide · The revised introduction and navigation for FAQs, wiki and resources.
Open originalsearch-indexedNo Sourcing
Moderator policy · The original moderator explanation of the sourcing rule.
Guidelines for Online Surveys and Research
Moderator policy · The public criteria for verified researchers and mod-approved studies.
Introduction to the r/Microdosing Research Library Collection
Moderator guide · The original collection introduction. Reddit retired its Collections feature in 2024.
Open originalsearch-indexed
The Wiki 8
Each chapter opens on Reddit with its original revision and attribution.
Wiki Index
Community wiki · The community’s navigation and context for using the wiki.
Effects, Side Effects and Interactions
Community wiki · The original discussion of reported effects, risks and interaction resources.
Microdose Preparation and Storage
Community wiki · Original historical page for preparation and storage, with community references.
Microdosing Dosage and Regimes
Community wiki · The original wiki page on patterns described by the community.
Mental Health
Community wiki · The original mental health and support resources.
Reports and Diaries
Community wiki · The wiki collection of first-person reports, logs and diaries.
Research Library
Community wiki · The original tables, study categories, media list and research notices.
Resources
Community wiki · The community’s additional reading, links and tools.
Selected Evidence 5
A reading route by study design. Check the population, comparator and outcome before applying a result.
Meshkat et al. · 2026
Systematic Review and Meta-Analysis · Psychological outcomes and safety in healthy adults. Includes 24 studies, with six contributing data to meta-analyses.
Totomanova et al. · 2025
Scoping Review · Maps benefits and risks discussed in 57 human studies.
Prochazkova et al. · 2025
Double-Blind Placebo-Controlled Studies · Two longitudinal psilocybin studies examining cognitive and subjective measures.
Cavanna et al. · 2022
Double-Blind Placebo-Controlled Study · Compares psilocybin microdosing and placebo across subjective, cognitive and other measures.
Szigeti et al. · 2021
Citizen Science Study · A self-blinded placebo-controlled citizen science study assessing expectancy and reported outcomes.
Sidebar Essentials 6
Named community FAQs and longer moderator posts in the sidebar.
What Should You Feel?
Sidebar FAQ
FAQ/Tip 101 · Finding Your Sweet Spot
Sidebar FAQ
FAQ/Tip 009 · LSD Preparation and Measurement
Sidebar FAQ
FAQ/Tip 017 · Timing and Food
Sidebar FAQ
FAQ/Tip 006 · Afterglow
Sidebar FAQ
FAQ/Tip 020 · Tolerance
Sidebar FAQ
Preparation, Storage and Substance FAQs 10
Historical records linked by the sidebar. Open each original for the date and context.
Shroomscout’s Guide
Historical sidebar FAQ
Bruising and Contamination
Historical sidebar FAQ
Capsules
Historical sidebar FAQ
Capsules Without a Capsule Machine
Historical sidebar FAQ
More on Capsules
Historical sidebar FAQ
Microdosing Truffles
Historical sidebar FAQ
Tea, Lemon Tek and Cacao FAQs
Historical sidebar FAQ
Stamets Stack · May 2022
Historical sidebar FAQ
Psilocybin FAQ
Historical sidebar FAQ
Microdosing Cannabis
Historical sidebar FAQ
Interactions, Symptoms and Harm Reduction 17
Community discussions and external harm reduction resources. For clinical questions, check the evidence and seek qualified advice.
Drug Interactions
Sidebar resource
FAQ/Tip 004 · LSD Interaction Checker and Caveats
Sidebar resource
Cannabis Interactions
Sidebar resource
Anxiety Attack
Sidebar resource
Nausea and Chitin
Sidebar resource
Vasoconstriction and Blood Pressure
Sidebar resource
Come-Up and Body Load
Sidebar resource
Afterglow and Irritability
Sidebar resource
Memory, Mood and Sleep
Sidebar resource
Anxiety and Depression
Sidebar resource
Community Discussion of Macro- and Microdosing Risks
Sidebar resource
Reagent Testing
Sidebar resource
Harm Reduction Apps
Sidebar resource
Drugs and Me
Sidebar resource
TripSafe
Sidebar resource
Zendo Project Support Resources
Sidebar resource
Erowid Psychedelic Crisis FAQ
Sidebar resource
Integration, Support and Tracking 13
Tools and conversations listed in the sidebar.
Self-Help Resources
Sidebar resource
Books
Sidebar resource
Self-Help Toons
Sidebar resource
Open originalaccess unverifiedIntegration and Therapy
Sidebar resource
Integration 101
Sidebar resource
Metacognition
Sidebar resource
Microbiome and Nutrition
Sidebar resource
Printable Microdose Tracker
Sidebar resource
Fireside Project Music
Sidebar resource
Fadiman and Gruber · 2025
Sidebar resource
Microdosing Book
Sidebar resource
Microdose.me AMA · 2022
Sidebar resource
Microdose.me Study
Sidebar resource
Research and Education 10
Topic feeds and collection routes maintained by the community.
Microdosing Research Feed
Research route
Data Science Feed
Research route
5-HT₂B Receptor · Community Post
Research route
Contribute to Research
Research route
Explain Like I’m Fiveish
Research route
Neuroplasticity
Research route
Pain Relief
Research route
Citizen Science
Research route
Citizen Science · Mobile Route
Research route
NeuronsToNirvana · Public r/microdosing Posts
Research route
Open Reddit author searchaccess unverified
Subreddit Flair Feeds 24
Live results from Reddit, including community reports, questions, research news and moderator posts.
Getting Started / Newbie Question
Reddit flair
Mod Post
Reddit flair
FAQ / Tips
Reddit flair
Discussion
Reddit flair
r/microINSIGHTS
Reddit flair
Question: LSD
Reddit flair
Question: Psilocybin
Reddit flair
Question: Other
Reddit flair
Report: LSD
Reddit flair
Report: Psilocybin
Reddit flair
Report: Other
Reddit flair
Research / News
Reddit flair
Contribute to Research
Reddit flair
Share Your Stack & Recipes
Reddit flair
r/microdosing Data Science
Reddit flair
Microdosing Research
Reddit flair
Microdosing Tools & Resources
Reddit flair
The Arts
Reddit flair
The Arts · For Review
Reddit flair
Meme Mondays
Reddit flair
Shit Post
Reddit flair
Just to Spread a Little Love and Positivity
Reddit flair
Contribute to Research · Under Review
Reddit flair
Contribute to Research · Ineligible
Reddit flair
Data Science Tables and Figures 32
Original Reddit excerpts with routes to publications, tables, figures and sources.
A Comprehensive Review of the Current Status of the Cellular Neurobiology of Psychedelics
Wiki research reference · Oct 2023
Reddit post Cited sourceaccess unverifiedTimeline
Wiki research reference · Aug 2023
A Brief Review on the Potential of Psychedelics for Treating Alzheimer’s Disease and Related Depression
Wiki research reference · Aug 2023
Reddit post Cited sourceaccess unverifiedLysergic Acid Diethylamide (LSD) Educational Review
Wiki research reference · Aug 2023
Reddit post Cited sourceaccess unverifiedPsychedelics and serotonin receptor signaling
Wiki research reference · Jan 2023
Reddit post Cited sourceaccess unverifiedTryptamine Potency Analysis of Psilocybe Mushrooms ✚ Further Analysis; Microdosing Ranges
Wiki research reference · Jan 2023
The Bright Side of Psychedelics: Latest Advances and Challenges in Neuropharmacology
Wiki research reference · Jan 2023
Micro-dose, macro-impact: Leveraging psychedelics in frontline healthcare workers during the COVID-19 pandemic
Wiki research reference · Dec 2022
The neural basis of psychedelic action
Wiki research reference · Nov 2022
1mg of psilocybin (microdose range) reduces MADRS Total Scores by Day 2 and Week 3
Wiki research reference · Nov 2022
Reddit post Cited sourceaccess unverifiedStructure–Activity Relationships for Psilocybin, Baeocystin, Aeruginascin, and Related Analogues to Produce Pharmacological Effects in Mice
Wiki research reference · Nov 2022
Mapping neurotransmitter systems to the structural and functional organization of the human neocortex
Wiki research reference · Oct 2022
Serotonin 5-HT2A, 5-HT2C and 5-HT1A receptor involvement in the acute effects of psilocybin in mice
Wiki research reference · Oct 2022
Timeline showing the earliest and latest observations of various changes in neuroplasticity following treatment with a single dose of the serotonergic psychedelics LSD, psilocybin/psilocin, DMT, or DOI
Wiki research reference · Sep 2022
Hamilton Depression Rating Scale (HDRS) score before and after starting psilocybin treatment: Microdosing Psilocybe cubensis (Fadiman Protocol)
Wiki research reference · Jul 2022
Contributions of psychedelic, dream and hypnagogic states to catalysing scientific creativity and insight
Wiki research reference · May 2022
Between receptor and mind: How psychedelics work on the brain
Wiki research reference · May 2022
More Evidence of the Chemical Compound Variability in Magic Mushrooms
Wiki research reference · Oct 2021
Reddit post Cited sourceaccess unverifiedFrom psychiatry to neurology: Psychedelics as prospective therapeutics for neurodegenerative disorders
Wiki research reference · Sep 2021
Preliminary tryptamine potency analysis from dried, homogenized fruit bodies of Psilocybe mushrooms incl. Caps Vs. Stems
Wiki research reference · May 2021
Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms
Wiki research reference · Jan 2021
Temperature stability of mushroom tryptamines from fungal homogenous powder which was heated in five replicates for 30 minutes
Wiki research reference · Oct 2020
Binding Affinities (Ki) of Serotonin vs. LSD at a few receptors: LSD binds to the 5-HT2A receptor 160x stronger than serotonin; 5-HT2B 12x stronger.
Wiki research reference · Aug 2020
Harvard Medical School: Antidepressant drugs and their half-lives
Wiki research reference
An overview of serotonin (5-HT) receptors that are stimulated by psilocin: Distribution, Physiological response (e.g. vasoconstriction / vasodilation), Behavioural responses.
Wiki research reference · Jul 2019
Psilocybin doses (in 3 mg capsules) and corresponding serotonin (5-HT) 2A receptor (2AR) occupancy estimates
Wiki research reference · Jan 2019
Reddit post Cited sourceaccess unverifiedBinding affinities for psilocybin and psilocin at 5-HT receptors
Wiki research reference · Aug 2018
Reddit post Cited sourceaccess unverifiedSemi-quantitative estimation of lysergamides on blotter samples
Wiki research reference · Jun 2016
Reddit post Cited sourceaccess unverifiedBinding of psilocin, DMT, LSD to 5-HT (serotonin) and other monoamine (adrenergic, dopamine, histamine) receptors
Wiki research reference · Jan 2011
Reddit post Cited sourceaccess unverifiedBinding affinities of LSD for various receptors
Wiki research reference · Jan 2006
Morphological and chemical analysis of magic mushrooms in Japan
Wiki research reference · Dec 2003
A comparison of maxima of psilocybin, psilocin and baeocystin in eleven species of Psilocybe
Wiki research reference
Articles and Studies 18
Research Library entries on medicines, mental health, genetics and other topics.
The Future of Psychedelics in Alzheimer's Disease Treatment
Wiki research reference · Jun 2021
Reddit post Articleaccess unverifiedPsychedelics as a Treatment for Alzheimer's Disease Dementia
Wiki research reference · Aug 2020
Acute Effects of Psilocybin After Escitalopram or Placebo Pretreatment in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Subjects
Wiki research reference · Nov 2021
A Single Dose of Psilocybin Increases Synaptic Density and Decreases 5-HT2A Receptor Density in the Pig Brain
Wiki research reference · Jan 2021
Cytochrome P450 enzymes contribute to the metabolism of LSD to nor-LSD and 2-oxo-3-hydroxy-LSD: Implications for clinical LSD use
Wiki research reference · Jun 2019
Psychedelics as a novel approach to treating autoimmune conditions
Wiki research reference · Dec 2020
Reddit post Reddit postaccess unverifiedCase Report: Resolution of Rheumatoid Arthritis in a Patient Consuming Psilocybin Mushrooms
Wiki research reference · Aug 2020
Analysis of blood mature BDNF and proBDNF in mood disorders with specific ELISA assays
Wiki research reference · Jan 2021
Low Doses of LSD Acutely Increase BDNF Blood Plasma Levels in Healthy Volunteers
Wiki research reference · Aug 2020
Modulation of Serum Brain-Derived Neurotrophic Factor by a Single Dose of Ayahuasca: Observation From a Randomized Controlled Trial
Wiki research reference · Jun 2019
5-HT2A SNPs Alter the Pharmacological Signaling of Potentially Therapeutic Psychedelics
Wiki research reference · Jul 2022
Genetic influence of CYP2D6 on pharmacokinetics and acute subjective effects of LSD in a pooled analysis
Wiki research reference · May 2021
Psilocybin for OCD (Obsessive Compulsive Disorder)
Wiki research reference · Jun 2021
Trial of Psilocybin versus Escitalopram for Depression
Wiki research reference · Apr 2021
Psychiatric Times: Psilocybin Revisited: The Science Behind the Drug and Its Surprising Therapeutic Potential
Wiki research reference · Mar 2021
Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder: A Randomized Clinical Trial
Wiki research reference · Nov 2020
Mood and cognition after administration of low LSD doses in healthy volunteers: A placebo controlled dose-effect finding study
Wiki research reference · Oct 2020
Trajectory of Antidepressant Effects after Single- or Two-Dose Administration of Psilocybin: A Systematic Review and Multivariate Meta-Analysis
Wiki research reference · Feb 2022
Microdosing Studies 13
Works specifically grouped under Microdosing by the original wiki.
Unlocking the self: Can microdosing psychedelics make one feel more authentic?
Wiki research reference · May 2023
Reddit post Paperaccess unverifiedExperiences of microdosing psychedelics in an attempt to support wellbeing and mental health
Wiki research reference · Mar 2023
The Effectiveness of Microdosed Psilocybin in the Treatment of Neuropsychiatric Lyme Disease: A Case Study
Wiki research reference · Mar 2023
Reddit post Paperaccess unverifiedThe emerging science of microdosing: A systematic review of research on low dose psychedelics (1955–2021) and recommendations for the field
Wiki research reference · Aug 2022
Global Drug Survey 2021: Some Microdosing Individuals Have Altered Psychiatric Drug Dosage
Wiki research reference · Feb 2022
Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers
Wiki research reference · Nov 2021
The therapeutic potential of microdosing psychedelics in depression
Wiki research reference · Aug 2020
Preliminary report on the effects of a low dose of LSD on resting state amygdalar functional connectivity
Wiki research reference · Apr 2020
Acute Subjective and Behavioral Effects of Microdoses of Lysergic Acid Diethylamide in Healthy Human Volunteers
Wiki research reference · Nov 2019
Microdosing psychedelics: More questions than answers? An overview and suggestions for future research
Wiki research reference · Jul 2019
A systematic study of microdosing psychedelics
Wiki research reference · Feb 2019
Psychedelic effects of psilocybin correlate with serotonin 2A receptor occupancy and plasma psilocin levels
Wiki research reference · Jan 2019
Exploring the effect of microdosing psychedelics on creativity in an open-label natural setting
Wiki research reference · Sep 2018
Neurology, Pain and Pharmacology 17
Contextual research listed by the wiki. Check each work’s population and intervention.
Psychedelics for Brain Injury: A Mini-Review
Wiki research reference · Jul 2021
Towards an understanding of psychedelic-induced neuroplasticity
Wiki research reference · Sep 2022
Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo
Wiki research reference · Jul 2021 · Jun 2021
Psychedelics Promote Structural and Functional Neural Plasticity
Wiki research reference · Jun 2018
Are psychedelics the answer to chronic pain: A review of current literature
Wiki research reference · Jan 2023
Psilocybin Use Associated With Lower Risk of Opioid Addictione
Wiki research reference · Apr 2022
A low dose of lysergic acid diethylamide decreases pain perception in healthy volunteers
Wiki research reference · Aug 2020
Psychedelics promote neuroplasticity through activation of intracellular 5-HT2A receptors
Wiki research reference · Feb 2023
Neuroscience research suggests LSD might enhance learning and memory by promoting brain plasticity
Wiki research reference · Aug 2022
Magic mushroom study hints psilocybin repairs alcohol-induced brain damage
Wiki research reference · Nov 2021
Tolerance to LSD – How the Brain Bolts the Doors of Perception
Wiki research reference · Oct 2021
Psychedelics: A New Fountain of Youth?
Wiki research reference · Jun 2021
Reddit post Articleaccess unverifiedOptimal dosing for psilocybin pharmacotherapy: Considering weight-adjusted and fixed dosing approaches
Wiki research reference · Feb 2021
"Repeated administration of low doses of the 5-HT2A agonist" LSD promotes social behavior(SB) through mTORC1 in the excitatory neurotransmission
Wiki research reference · Jan 2021
Pharmacological and biotransformation studies of 1-acyl-substituted derivatives of d-lysergic acid diethylamide (LSD)
Wiki research reference · Aug 2020
Why Magic Mushrooms Get The Blues ?
Wiki research reference · Nov 2019
Stability Study of LSD Under Various Storage Conditions
Wiki research reference · Oct 1998
Audio and Video 28
Documentaries, interviews and talks listed by the wiki. Check transcripts and original papers when using them as evidence.
Magic Mushroom Medical Trial (Medical Documentary)
Wiki media reference · Nov 2020
Microdosing: People who take LSD with breakfast - BBC News
Wiki media reference · Apr 2017
How To Change Your Mind
Wiki media reference · Jul 2022
Descending The Mountain
Wiki media reference · Sep 2021
Have A Good Trip
Wiki media reference · May 2020
Fantastic Fungi
Wiki media reference · 2019
Neurons to Nirvana - Understanding Psychedelic Medicines
Wiki media reference · 2013
MAPS Podcast hosted by Zach Leary
Wiki media reference
Psychedelics, Microdosing Psilocybin, Stress Resilience, Anxiety & OCD
Wiki media reference · Oct 2023
Find in the original wikiwiki referenceAll About Microdosing: New Findings & New Uses with Dr James Fadiman
Wiki media reference · Jul 2023
Original publisher Find in the original wikiwiki referenceThe Science of Psychedelics & Microdosing, ft. Dr. James Fadiman
Wiki media reference · Jan 2023
Find in the original wikiwiki referenceJames Fadiman, Ph.D., Adam Bramlage, & Conor Murray, Ph.D. – Microdosing & Citizen Science : Introducing the World’s First Take-Home EEG Microdosing Study
Wiki media reference · Dec 2022
Original publisher Find in the original wikiwiki referenceThe Art of Microdosing Q+A with Dr. James Fadiman & Adam Bramlage
Wiki media reference · Oct 2022
Original publisher Find in the original wikiwiki referenceMicrodosing with James Fadiman
Wiki media reference · Feb 2022
Find in the original wikiwiki referenceDr. Matthew Johnson (Johns Hopkins School of Medicine): Psychedelics for Treating Mental Disorders
Wiki media reference · Sep 2021
Original publisher Find in the original wikiwiki referenceJames Fadiman, Adam Bramlage & Fireside Project's Co-Founders on Microdosing Risk Reduction
Wiki media reference · Jun 2021
Find in the original wikiwiki referenceComes a Time Podcast (Episode 42): Dr. James Fadiman
Wiki media reference · Apr 2021
Find in the original wikiwiki referenceBen Greenfield Fitness: Microdosing For Sports Performance, Microdosing Stacks With Psychedelics & Plant Medicines, The Best Microdosing Protocols & Much More With James Fadiman
Wiki media reference · Feb 2021
Find in the original wikiwiki referenceThe Art of Microdosing with James Fadiman & Adam Bramlage
Wiki media reference · Dec 2020
Find in the original wikiwiki referencePlant Medicine Podcast: Microdosing Q&A with James Fadiman
Wiki media reference · Aug 2020
Original publisher Find in the original wikiwiki referenceThe Benefits of Micro-dosing Mushrooms w/Paul Stamets
Wiki media reference · Nov 2019
Find in the original wikiwiki referencePsychedelic Microdosing: A Panel Discussion on Science and Stories
Wiki media reference · May 2023
Original publisher Find in the original wikiwiki referencePaul Stamets – Psilocybin Mushroom Medicines: A Paradigm Shift in Global Consciousnesss
Wiki media reference · Jan 2021
Find in the original wikiwiki referencePaul Stamets at the Psilocybin Summit 2020 - Psilocybin Mushrooms & Their Emergent Medicines
Wiki media reference · Nov 2020
Find in the original wikiwiki reference'Why do LSD trips last so long?' with structure and biochemistry
Wiki media reference · Aug 2020
Original video Find in the original wikiwiki referenceThe Remarkable Results of Microdosing: James Fadiman
Wiki media reference · Apr 2019
Find in the original wikiwiki referenceMicrodosing: The Benefits, Risks, & Unknowns w/ Jim Fadiman & Ayelet Waldman
Wiki media reference · Oct 2018
Original publisher Find in the original wikiwiki referenceLife changing magic mushroom (psilocybin) experience - Paul Stamets
Wiki media reference · Feb 2015
Find in the original wikiwiki reference
Further Research and Contributions 10
Search paths from the Research Library and routes for new contributions.
ClinicalTrials.gov · Microdosing Results
Trial registry · Search the original registry record, protocol and updates.
ClinicalTrials.gov · LSD
Trial registry · Original wiki search term.
ClinicalTrials.gov · Psilocybin
Trial registry · Original wiki search term.
ClinicalTrials.gov · Psychedelics
Trial registry · Original wiki search term.
MAPS Psychedelic Bibliography
Research route
MAPS Resources and Multimedia
Research route
Paul Stamets · Peer-Reviewed Scientific Articles
Research route
r/PsychedelicStudies
Research route
Research Contribution Opportunities
Wiki section · The original archive of calls, past studies and contributions.
Microdosing Survey Findings
Wiki section · The community’s original report of its research contributions.
Open originalwiki reference
Scope and Access
This snapshot covers the public subreddit navigation, sidebar, wiki chapters and the entries catalogued from the Research Library index. The flair links reopen live Reddit searches. The index includes several newer studies and reviews under Selected Evidence.
Each card links back to the publicly listed original or its wiki entry. Search-indexed and access-unverified sources are marked at the link. Historical media and recruitment entries may have moved. The archive omits deleted, private and unindexed threads and the text of individual community reports.
Community posts record experience and practice. Controlled studies answer questions about their own populations, comparisons and outcomes. Use the source type and study design to judge what each can establish.
r/microdosing · Original Wiki Index · Original Research Library